Ramon Jin, MD PhD

Senior Fellow

Hometown: Cleveland, Ohio
Medical School: Washington University in St. Louis
Residency: Washington University in St. Louis/Barnes-Jewish Hospital
Research/Academic Interests: My studies will elucidate basic and therapeutically relevant principles of upper GI cancers from new genetic, developmental, and cell biological perspectives.
Bio: I like collecting sports memorabilia, collecting basketball shoes, fast loud JDM cars, pickup basketball, playing piano, and learning to mix vinyl records.

Selected Publications/Abstracts

  • Jin RU, Mills JC. Tumor Organoids to Study Gastroesophageal Cancer: A Primer. J Mol Cell Biol 2020 Jul 11; [Epub ahead of print]
  • Park H, Jin RU, Wang-Gillam A, Suresh R, Rigden C, Amin M, Tan BR, Pedersen KS, Lim KH, Trikalinos NA, Acharya A, Copsey ML, Navo KA, Morton AE, Gao F, Lockhart AC. FOLFIRINOX for the Treatment of Advanced Gastroesophageal Cancers: A Phase 2 Nonrandomized Clinical Trial. JAMA Oncol 2020 May 29; [Epub ahead of print]
  • Jacobs MT, Olson M, Ferreira BP, Jin RU, Hachem R, Byers D, Witt C, Ghobadi A, DiPersio JF, Pusic I. The Use of Ruxolitinib for Acute Graft-Versus-Host Disease Developing After Solid Organ Transplantation. Am J Transplant 2020 Feb;20(2):589-592
  • Jin RU, Mills JC. The Cyclical Hit Model: How Paligenosis Might Establish the Mutational Landscape in Barrett’s Esophagus and Esophageal Adenocarcinoma. Curr Opin Gastroenterol 2019 Apr 22; [Epub ahead of print]
  • Jin RU, Mills JC. Are Gastric and Esophageal Metaplasia Relatives? The Case for Barrett’s Stemming From SPEM. Dig Dis Sci 2018 Aug;63(8):2028-2041
  • Lo HG, Jin RU, Sibbel G, Liu D, Karki A, Joens MS, Madison BB, Zhang B, Blanc V, Fitzpatrick JA, Davidson NO, Konieczny SF, Mills JC. A Single Transcription Factor Is Sufficient to Induce and Maintain Secretory Cell Architecture. Genes Dev 2017 Jan 15;31(2):154-171
  • Moore BD, Jin RU, Lo H, Jung M, Wang H, Battle MA, Wollheim CB, Urano F, Mills JC. Transcriptional Regulation of X-Box-Binding Protein One (XBP1) by Hepatocyte Nuclear Factor 4alpha (HNF4alpha) Is Vital to Beta-Cell Function. J Biol Chem 2016 Mar 18;291(12):6146-57
  • Moore BD, Jin RU, Osaki L, Romero-Gallo J, Noto J, Peek RM Jr, Mills JC. Identification of Alanyl Aminopeptidase (CD13) as a Surface Marker for Isolation of Mature Gastric Zymogenic Chief Cells. Am J Physiol Gastrointest Liver Physiol 2015 Dec 15;309(12):G955-64
  • Jin RU, Mills JC. RAB26 Coordinates Lysosome Traffic and Mitochondrial Localization. J Cell Sci 2014 Mar 1;127(Pt 5):1018-32
  • Jin RU, Mills JC. The Ubiquitin Ligase Mindbomb 1 Coordinates Gastrointestinal Secretory Cell Maturation. J Clin Invest 2013 Apr;123(4):1475-91
  • Yin Y, Lin C, Kim ST, Roig I, Chen H, Liu L, Veith GM, Jin RU, Keeney S, Jasin M, Moley K, Zhou P, Ma L. The E3 Ubiquitin Ligase Cullin 4A Regulates Meiotic Progression in Mouse Spermatogenesis. Dev Biol 2011 Aug 1;356(1):51-62
  • Tian X, Jin RU, Bredemeyer AJ, Oates EJ, Blazewska KM, McKenna CE, Mills JC. RAB26 and RAB3D Are Direct Transcriptional Targets of MIST1 That Regulate Exocrine Granule Maturation. Mol Cell Biol 2010 Mar;30(5):1269-84
  • Jin RU, Hodges CA, Drumm ML, Palmert MR. The Cystic Fibrosis Transmembrane Conductance Regulator (Cftr) Modulates the Timing of Puberty in Mice. The Journal of Medical Genetics 2006 Jun;43(6):e29
  • Jin RU, Mills JC. Chapter 5: Congenital and Acquired Diseases of the Stomach. In: DL Gumucio, LC Samuelson, JR Spence (Eds), Translational Gastroenterology: Organogenesis to Disease (pp 57-71). Hoboken: John Wiley and Sons, 2014